24hrdoc Team|Common Medical|October 22, 2025

The holidays bring joy, family, and plenty of food—but for those on GLP-1 medications, the celebrations can come with a few extra challenges. Rich meals, desserts, and alcohol can make side effects like nausea, bloating, or fatigue more noticeable. With a few smart GLP-1 tips, you can still enjoy every gathering and focus on holiday healthy foods that help you feel your best.

Why Holiday Eating Hits Hard on GLP-1

GLP-1 medications like semaglutide and tirzepatide slow down digestion to help control appetite and blood sugar. That’s what makes them so effective for weight loss, but it also means heavy or high-fat meals linger longer in the stomach.

During the holidays, when dishes are loaded with butter, sugar, and cream, this slower digestion can make you feel overly full, nauseous, or uncomfortable. Overeating or eating too fast often intensifies these symptoms. The key is pacing yourself and prioritizing the most ideal foods to eat while on GLP-1, such as lean proteins, vegetables, and fiber-rich sides, while limiting foods to avoid on GLP-1, like greasy, creamy, or sugary dishes.

Five Rules for Eating on GLP-1 During the Holidays

The holidays don’t have to mean abandoning your healthy routine. These simple GLP-1 tips can help you enjoy healthy holiday food without unwanted side effects..

  1. Eat slowly: Take small bites and chew well. It gives your body time to register fullness and helps prevent nausea.
  2. Keep portions small: Try a little of everything you enjoy instead of full servings of every dish.
  3. Prioritize protein: Lean turkey, chicken, fish, or plant-based proteins help you feel satisfied longer without overloading your stomach.
  4. Skip seconds (for now): Wait at least 20 minutes before deciding if you want more. You’ll often find you’re full.
  5. Listen to your body: Stop eating when you feel comfortable rather than pushing through just because it’s a special occasion.

How to Build a GLP-1 Friendly Holiday Plate

Think balance, not restriction. The American Diabetes Association’s Diabetes Plate Method is a simple and effective way to guide your holiday meals, especially if you’re on GLP-1 therapy. It also aligns with the best foods to eat on GLP-1, helping you enjoy healthy holiday food without discomfort.

Fill half your plate with non-starchy vegetables such as green beans, salad, or roasted Brussels sprouts. Reserve one-quarter of your plate for lean protein like turkey, chicken, or tofu. Use the final quarter for healthy carbohydrates—a small serving of mashed potatoes, stuffing, or a dinner roll.

This balanced approach helps maintain steady blood sugar levels while minimizing the risk of nausea or bloating. Add a small portion of your favorite dessert if you want one, but avoid piling on multiple rich dishes or creamy sauces at once. By keeping balance and pacing in mind, you can enjoy every bite without discomfort.

Foods That Commonly Trigger Symptoms on GLP-1s

While everyone’s tolerance is different, some foods are more likely to cause nausea or bloating. The most common foods to avoid on GLP-1 include:

  • Fried foods or greasy appetizers
  • Creamy casseroles and cheese-based dips
  • Sugary desserts like pies, cheesecakes, and puddings
  • Carbonated or sugary drinks
  • Processed meats and salty snacks

Choosing simpler holiday healthy foods and eating mindfully can help you feel more comfortable while still enjoying seasonal flavors.

Close up on a Thanksgiving plate of food

What to Do if You Feel Too Full or Nauseated

Feeling overly full or queasy after eating is common while on GLP-1 medications, especially during big holiday meals. If it happens, start by pausing and giving your body time to settle—don’t try to push through more food or drink. Take slow, deep breaths and sit upright to help your stomach empty more comfortably.

Sip water or warm tea in small amounts to stay hydrated, but avoid carbonated beverages that can increase bloating. Gentle movement, like a short walk, can also ease discomfort. If symptoms persist or become severe, skip your next planned meal until you feel ready to eat again, and focus on light foods such as broth, toast, or plain rice when you resume eating.

If nausea is frequent or worsening, it’s worth checking in with your prescribing clinician, who may adjust your dosage or recommend supportive medication.

Drinking Alcohol While on GLP-1

Alcohol affects the body differently when you’re taking GLP-1 medications. Because these drugs slow digestion, alcohol can hit your system faster and may worsen nausea or dehydration.

If you decide to drink, do so slowly and always with food to help absorb the alcohol more evenly. Choose lighter options such as a glass of wine or a vodka soda instead of sugary cocktails, and alternate each drink with water. Staying hydrated throughout the day will help prevent dizziness and fatigue so you can enjoy the festivities comfortably and safely.

Frequently Asked Questions

Should you pause your GLP-1 for the holidays?

Not usually. Unless your healthcare provider advises otherwise, it’s best to stay consistent. Pausing your medication can lead to side effects when restarting.

Is there a specific “Ozempic holiday diet”?

There isn’t an official Ozempic or GLP-1 holiday diet. The best approach is to follow balanced eating guidelines, like the Diabetes Plate Method to stay comfortable while still enjoying your favorite holiday foods.

What if I forget my weekly GLP-1 dose while traveling?

If you remember within two or three days of your scheduled time, take it then. If it’s been longer, skip the missed dose and resume your normal schedule.

Enjoy the Holidays, Stay on Track

With a thoughtful approach to meals and mindful habits, you can enjoy the holidays without the discomfort that sometimes comes with GLP-1 use.

If you’re ready to start your own weight loss journey—or want to stay consistent year-round—24hrdoc makes it easy to get weight loss medication online. Our licensed medical providers prescribe semaglutide and tirzepatide with personalized care coaching to help you reach your goals safely and effectively, no matter the season.

References

Harvard Health Publishing. How does Ozempic work? Understanding GLP-1s for diabetes, weight loss, and beyond.

American Diabetes Association. What is the Diabetes Plate?.