Oral Semaglutide

Oral semaglutide is the first and only GLP-1 receptor agonist available in pill form. It works by mimicking a natural hormone that helps control blood sugar, slow digestion, and reduce hunger signals in your brain.
Unlike the injectable version, oral semaglutide offers the same clinical benefits in a once-daily tablet—making it a more convenient option for people who prefer not to use injections.

Oral semaglutide is prescribed to help adults with type 2 diabetes manage their blood sugar. It may also support weight loss in some cases, under medical supervision.

• Managing type 2 diabetes
• Supporting weight loss
• Controlling post-meal blood sugar spikes
• Improving long-term metabolic health
  
  
  
  

Common side effects of oral semaglutide

• Nausea
• Vomiting
• Diarrhea
• Constipation
• Headache
• Fatigue
• Stomach pain

Oral semaglutide is taken as a once-daily tablet, available in the following strengths:

• 3 mg (starter dose)
• 7 mg
• 14 mg

Patients typically begin with a lower dose to reduce side effects, then gradually increase based on response and provider guidance.

To get the most benefit, oral semaglutide should be taken first thing in the morning, with a small amount of water, and on an empty stomach.

Tips:

• Take with no more than 4 oz of plain water
• Wait at least 30 minutes before eating or drinking anything else
• Take at the same time each day
• Don’t crush or chew the tablet
• Follow your provider’s instructions for dose escalation

Oral semaglutide should not be used by individuals with a personal or family history of medullary thyroid cancer or MEN 2 syndrome. These are rare conditions but are associated with a higher risk of thyroid-related side effects.

It’s also not recommended if you’ve experienced a serious allergic reaction to semaglutide or any of the ingredients in the pill. Let your 24hrDoc provider know if you have a history of pancreatitis, kidney problems, or gastrointestinal disease.